Executive Director , Multiple Myeloma Disease Head
Company: Disability Solutions
Location: Cambridge
Posted on: May 3, 2024
Job Description:
Working with UsChallenging. Meaningful. Life-changing. Those
aren't words that are usually associated with a job. But working at
Bristol Myers Squibb is anything but usual. Here, uniquely
interesting work happens every day, in every department. From
optimizing a production line to the latest breakthroughs in cell
therapy, this is work that transforms the lives of patients, and
the careers of those who do it. You'll get the chance to grow and
thrive through opportunities uncommon in scale and scope, alongside
high-achieving teams rich in diversity. Take your career farther
than you thought possible.Bristol Myers Squibb recognizes the
importance of balance and flexibility in our work environment. We
offer a wide variety of competitive benefits, services and programs
that provide our employees with the resources to pursue their
goals, both at work and in their personal lives. Read more:
careers.bms.com/working-with-us .Title: Executive Director ,
Multiple Myeloma Disease HeadTranslational Medicine at BMS
Translational Medicine is part of the Global Research and Early
Development organization in BMS and leads early stage clinical,
pharmacological and translational research and development
activities for the pipeline and supports late stage portfolio for
regulatory, translational development and life cycle management.
The Heme Translational Medicine Disease Team (TMDT) is a late
translational group that supports multiple disease areas of
interest including Myeloma, Myeloid, Lymphoma, Erythroid disorders,
and other hematological malignancies. This group integrates
scientific and business insights of multiple functions and leads
the development of translational strategies at the franchise level
and implements them in project teams to maximize the potential of
BMS drugs.Summary:Reporting to the VP, Hematology Translational
Medicine, the incumbent will be part of the translational group
based in Summit NJ and will help develop translational disease and
asset strategies in Multiple Myeloma or Myeloid/Erythroid disease
areas for assigned programs for approval or life-cycle management
of the BMS pipeline. Key responsibility of this role is to lead the
Myeloma disease team consisting of a cross functional team of asset
and disease scientists with deep disease, drug development and
business knowledge for overall translational strategy working
closely with discovery and early development teams, late clinical
development as well as with a hematology laboratory group.Technical
Skills:
- In-depth understanding of Oncology or Hematological cancers,
especially Multiple Myeloma, , clinical landscape, evolving
therapy, competitive landscape
- Strong understanding of clinical, translational and mechanistic
data with therapeutics development
- Strong background in genetics, cancer biology and/or
immunology
- Strong background in strategy development preferably in
hematology
- Understanding of late-stage drug and translational development
process --- Proven track record of drug submissions, approvals,
regulatory interactions and label negotiations
- Proven ability to work with global disease teams to develop
strategies to support life cycle management efforts tailored to
regional markets (i.e, US, EU, CAN) bms.com/careers
- Strong verbal and written communication skills with experience
in developing written documents such as primary
manuscripts/publications/reviews, disease strategies, mechanism
slides, regulatory submissions, strategic communications,
literature/market/pt segment analyses --- Proven scientific/project
leadership expertise (working in teams, managing
people/projects)
- Ability to synthesize complex scientific and business problems
into strategy and tactics
- Basic understanding of IP, contracting terms and
provisionsResponsibilities: In coordination with Head of Strategy
and Execution, builds disease area specific long term translational
strategy and implementation across portfolio:
- Leads the development of disease, portfolio, or asset specific
translational annual goals and objectives for the Heme TMDT (for
internal /external, translational collaboration, compound specific
plans etc), open research questions, and is accountable for their
progress monitoring in association with Heme TMDT asset and disease
scientists
- Assists in developing and maintaining group budget and
workforce plan
- Represents Translational Medicine (TM) in cross-functional
Strategy and Global Project Teams
- Interfaces with commercial including early commercialization
group and Medical Affairs to provide scientific support for
cross-functional TM goals
- Assists in managing key strategic and/or collaborative projects
along with TM scientists
- Supports regulatory submissions, regulatory interactions,
writes translational sections for regulatory response and answers
to regulatory queries for the TM group
- Communicates regularly and prepares and makes presentations
within the department and externally as required
- Participates in translational research with the Heme TMDT
Lab
- Oversees genomic analyses from human clinical samples, cell
screens (ie, for resistance mechanisms, PD, biomarkers) and
clinical trial support (defined clinical experiments from the
development teams). This includes development of high dimensional
bioinformatics in collaboration with the Informatics and Predictive
Sciences group
- Responsible for delivery of Clinical PD or Biomarker assays,
translated from discovery (if applicable or appropriate) or
developed specifically for early clinical use, assessing
feasibility and applicability for companion diagnostics
- Application of model systems (in collaboration with the disease
biology and in vivo pharmacology groups) beyond those routinely
employed by discovery teams that aid in patient
stratification/response and compound use, either in-house or as a
collaboration --- Participates in formulating disease area strategy
for target selection and validation
- Evaluating, in conjunction with BD and established teams, the
potential for in-licensing opportunities that may include potential
therapeutics, emerging technologies, processes or capabilities that
will enhance our Drug Discovery and Early Development efforts
- Be part of the team responsible for establishing key alliances
with academic centers, co-operative groups and government agencies
for cost effective implementation of BMS early and late development
strategy
- May perform advisory and mentoring role for junior scientists
--- Supports MRD efforts across Heme area
- Liaises with key BMS Research and Early Development thematic
centers of excellence to help formulate and execute on new
hypotheses driving new clinical biomarker assays for unmet need
segments, disease strategy for new targets and development
candidates and ensure seamless transition of patient selection
strategies beyond Phase 1
- Serves as translational representative on BMS cross functional
Disease Strategy Team and interfaces with commercial, clinical,
Project leadership and regulatory teams to define patient segments
of unmet need based on rapidly evolving clinical programs and
commercial landscape
- Leads small and large collaborations with academia and industry
partners to identify biobanks, clinical trials and existing
databases to collate multi-parameter genomic and clinical datasets
to mine for novel biomarkers of unmet need patients in conjunction
with computational biologists, data scientists and
statisticianSummary: The candidate will be at the interface with
asset, disease and lab teams, with the aim of providing the
successful implementation of translational strategies in BMS
pipeline developmentQualifications:
- MD/PhD in Hematology/Oncology or related field with minimum
12-15 years in industry or industry plus academic setting
- Track record in large and small companies, leading innovative
efforts to deploy technologies and assays for enhanced
translational capabilities
- Excellent communication, managerial and scientific qualities
are expected
- Ability to interact effectively across boundaries using
influencing and relationship building skills.
- Competence in analysis and solving of problems, and the ability
to prioritize and make tradeoffs to achieve goals.
- Other Attributes: A problem solver who creatively and
knowledgably transcends departmental function to act as a resource
to entire research effort and senior managers in development.
- Identifies issues early and proposes innovative solutions.
- Communicates within the larger organization and external
community.
- Provides expert guidance to multi-disciplinary teams and senior
management.
- A leader whose scope of influence stretches across BMS.
- A leader who influences external scientific community.
- Expertise in the integration of preclinical research and
clinical drug development
- Ability to lead basic research programs as well as development
and execution of clinical correlative science strategies
- Management experience with the ability to set priorities,
direct projects and implement complex strategies and work on
cross-functional team
- Highly effective teamwork and interpersonal skills and the
ability to work across numerous scientific disciplines If you come
across a role that intrigues you but doesn't perfectly line up with
your resume, we encourage you to apply anyway. You could be one
step away from work that will transform your life and career.
Uniquely Interesting Work, Life-changing CareersWith a single
vision as inspiring as Transforming patients' lives through
science--- , every BMS employee plays an integral role in work that
goes far beyond ordinary. Each of us is empowered to apply our
individual talents and unique perspectives in an inclusive culture,
promoting diversity in clinical trials, while our shared values of
passion, innovation, urgency, accountability, inclusion and
integrity bring out the highest potential of each of our
colleagues.On-site Protocol BMS has a diverse occupancy structure
that determines where an employee is required to conduct their
work. This structure includes site-essential, site-by-design,
field-based and remote-by-design jobs. The occupancy type that you
are assigned is determined by the nature and responsibilities of
your role: Site-essential roles require 100% of shifts onsite at
your assigned facility. Site-by-design roles may be eligible for a
hybrid work model with at least 50% onsite at your assigned
facility. For these roles, onsite presence is considered an
essential job function and is critical to collaboration,
innovation, productivity, and a positive Company culture. For
field-based and remote-by-design roles the ability to physically
travel to visit customers, patients or business partners and to
attend meetings on behalf of BMS as directed is an essential job
function. BMS is dedicated to ensuring that people with
disabilities can excel through a transparent recruitment process,
reasonable workplace accommodations/adjustments and ongoing support
in their roles. Applicants can request a reasonable workplace
accommodation/adjustment prior to accepting a job offer. If you
require reasonable accommodations/adjustments in completing this
application, or in any part of the recruitment process, direct your
inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/
eeo -accessibility to access our complete Equal Employment
Opportunity statement. BMS cares about your well-being and the
well-being of our staff, customers, patients, and communities. As a
result, the Company strongly recommends that all employees be fully
vaccinated for Covid-19 and keep up to date with Covid-19 boosters.
BMS will consider for employment qualified applicants with arrest
and conviction records, pursuant to applicable laws in your
area.Any data processed in connection with role applications will
be treated in accordance with applicable data privacy policies and
regulations.
Keywords: Disability Solutions, Waltham , Executive Director , Multiple Myeloma Disease Head, Executive , Cambridge, Massachusetts
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