Scientist/ Sr. Scientist, Protein Biochemistry

Company: Morphic Therapeutic
Location: Waltham
Posted on: March 22, 2020

Job Description:

About Morphic Therapeutic Morphic Therapeutic is a biopharmaceutical company developing a new generation of oral integrin therapies for the treatment of serious chronic diseases, including autoimmune, cardiovascular and metabolic diseases, fibrosis and cancer. In collaboration with AbbVie, Janssen and Schrödinger, Morphic is advancing its pipeline and discovery activities using its proprietary MInT technology platform which leverages the Company’s unique understanding of integrin structure and biology. For more information, visit www.morphictx.com . Morphic is advancing both partnered and fully-owned oral integrin therapeutic candidates into the clinic with an anticipated first IND filing mid-2020. Our immediate focus is on the areas where the clinical activity of antibody inhibitors of integrins is precedented, thus enabling a rapid path to clinical proof-of-concept. The Morphic Therapeutic office is located in the AstraZeneca BioHub in Waltham, MA. We are seeking a highly talented and motivated individual to join our culture of teamwork, craftsmanship, tenacity, compassion, and integrity. Job description Morphic Therapeutic is seeking an accomplished, innovative, and motivated Protein Biochemist. The position will be part of a multi-discip linary team at Morphic, working together towards transformative small molecule therapeutics for autoimmune and fibrotic diseases, as well as immuno-oncology. A strong track record of working with highly challenging protein targets or biologics is required. Responsibilities • Construct design/expression/purification of novel integrin complexes and other challenging proteins using mammalian cells • Developing constructs and cell lines for biophysical and biochemical assays • Working with crystallographers to design experiments for structural studies • Production of recombinant antibodies, fusion proteins, and other biologics for in vivo studies • Present results (written and oral) to internal and external audiences • Mentoring and developing junior staff YourMembership. Keywords: Senior Scientist, Location: Waltham, MA - 02451

Keywords: Morphic Therapeutic, Waltham , Scientist/ Sr. Scientist, Protein Biochemistry, Other , Waltham, Massachusetts