Job description Site Name: USA - Massachusetts - Waltham, USA -
Pennsylvania - Upper Providence
Posted Date: Jun 8 2020
Are you an R & D pharmaceutical executive who has a strategic
portfolio mindset and are able to engage stakeholders in a complex
environment while providing great leadership and governance? If so
and you are a re interested in a highly visible role, this could be
an ideal opportunity to explore.
GSK’s Pharmaceutical Medicines business:
GSK's pharmaceutical medicines business has a broad portfolio of
innovative and established medicines. Currently, we are focusing on
developing new medicines in Oncology, Immuno-Inflammation,
Respiratory, and HIV/Infectious Diseases. The rebuilding of our
Pharmaceuticals pipeline continues with most of our new medicines
in development targeting modulation of the immune system. Major
progress has been made in our immuno-oncology pipeline with assets
now in clinical development, reflecting organic progression, our
recent acquisition of Tesaro, Inc., and our new global strategic
alliance with Merck KGaA, also known as EMD Serono in the U.S.
GSK Oncology R&D is focused on building industry-leading
portfolios in four cutting-edge areas of science:
• Immuno-Oncology : using the human immune system to treat
• Cell/Gene Therapy : engineering human T-cells to target
• Cancer Epigenetics : modulating the gene-regulatory
system of the epigenome to exert anti-cancer effects
• Synthetic Lethality : targeting two mechanisms at the
same time which together, but not alone, have substantial effects
For more Information on GSK Oncology, please visit:
2019 Annual Report:
The Head, Medicine Development Leaders MDLs) is a critical role
within the GSK R&D Oncology organisation and reports to the SVP
Oncology R & D and sits on the Oncology Leadership Team. The
appointee will strategically and operationally manage and lead the
Medicine Development Leaders group across R&D Oncology,
providing global leadership and guidance across the group, and
ensuring best practice and high levels of quality in clinical
development. The Head, MDLs will broaden and increase the skill set
of the MDL group, bringing the team together through coaching,
mentoring and development.
Head of MDLs will strategically lead the optimal global
development of medicines across the portfolio, substantially
contributing and influencing from pre-C2P2 to post-launch
life-cycle management, to ultimately deliver differentiated
medicines of value.
By working with the various stakeholders across R&D and
Pharma, Head of MDLs will define the strategic vision and
operational plan for medicines, aligning it with the overall
Provide strong and effective leadership to the global MDL group
(VP level MDLs). Foster and develop an environment of best practice
and high-quality drug development within the global MDL group.
Establish a compelling vision for the MDL team; positioning the
team within the R&D strategy and ensuring professional
Own the performance of the MDLs to drive success. Coach and
mentor the MDL team to bring out the best in the team and continue
to develop the skillsets required for the MDL role – this is of
particular significance as the MDL is the key decision maker on
critical develop projects and thus needs to be provided with the
tools and confidence to make such decisions.
Ensure the MDLs deliver the Medicine Development Strategy that
is aligned with the R&D disease strategy.
Provide leadership and guidance to the MDL team to ensure a
smooth transition between the EDL (accountable from Candidate
Selection to Proof of Concept, Phase 1) to MDL (accountable from
Phase 2 to approval in first major market) and from MDL to MCL
(accountable from approval in first major market).
Provide guidance to the MDLs when providing key support to the
EDT leading up to C2P2 to ensure smooth transfer of accountability
and a successful C2P2 and transition from phase 1 to phase 2.
Provide leadership and guidance to the MDLs on selecting members
of the Medicines Development Team (MDT), as well as the leadership
of this multi-disciplinary matrix team; support differentiated
development for team members.
Provide leadership and guidance to the MDLs in establishing a
compelling vision for the relevant medicine; assist in the
positioning of the medicine within the R&D strategy taking the
competitive landscape into account.
Ensure the GSK strategy is translated effectively into asset
strategy and actionable plans for multiple areas or functions by
Ensure success in delivering differentiated medicines of value
for patients, stakeholders and markets, through an evidence package
that supports regulatory approval, market access, and product life
We are looking for professionals with these required skills to
achieve our goals:
Pharm D, PhD or MD
Filing experience BLA/NDA/ MAA submissions as a core
responsibility and have led development programs.
· Must demonstrate extensive broad drug development expertise
· Considerable pharmaceutical industry experience is
· Prior significant experience in leading successful development
and registration of medicines is highly preferred.
· Deep experience in product development and/or commercial,
especially in late phase development (from PoC onwards), clinical
trial management with significant operational complexity,
post-approval studies, regulatory and manufacturing compliance.
· Highly developed ethics and integrity, with demonstrated
ethical medical decision-making skills.
· Understands the entirety of R&D across the
development/commercial life cycle to allow impact across all
functions: discovery, late stage development, regulatory,
manufacturing and commercial.
Significant rack record of success working in highly complex,
matrixed, global, and multi-disciplinary organization with high
accountability, minimal authority, and multiple lines of
Strategic Portfolio Mindset: ability to develop a deep
understanding of GSK global strategies, identify how these can be
applied, leveraged and adapted across local-regional contexts
whilst fostering innovation.
Project Leadership and Governance: effectively manage different
business functions and create alignment between different project
indications and asset teams with different objectives.
Engaging Stakeholders in a Complex Environment: utilise
organizational channels, experience and influencing skills to
facilitate successful project progression and effective issue
If you have the following characteristics, it would be a
Demonstrates the discipline of risk-based planning, organising
and managing matrix resources to bring about the successful
completion of complex programmes and objectives in accordance with
defined quality and time-based metrics.
Maintains competitive advantage by carefully considering the
issues and competing priorities within a situation, program or
portfolio and then developing a strategy that includes the
strategic application of available principles, tools and
Our values and expectations are at the heart of everything
we do and form an important part of our culture.
These include Patient focus, Transparency, Respect, Integrity
along with Courage, Accountability, Development, and Teamwork. As
GSK focuses on our values and expectations and a culture of
innovation, performance, and trust, the successful candidate will
demonstrate the following capabilities:
Agile and distributed decision-making – using evidence and
applying judgement to balance pace, rigour and risk, governance and
control, managing ambiguity and paradox.
Managing individual performance.
Creating a performance culture and driving results,
prioritisation, execution, delivering performance.
Setting strategic direction and leading on-going organisational
Building a resilient organisation.
Building strong relationships and collaboration in service of
common goals, engaging the organisation and building trusted
external networks for mutual benefit.
Managing P&L and capital allocation.
If you require an accommodation or other assistance to apply for
a job at GSK, please contact the GSK Service Centre at
1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).
GSK is an Equal Opportunity Employer and, in the US, we adhere
to Affirmative Action principles. This ensures that all qualified
applicants will receive equal consideration for employment without
regard to race, color, national origin, religion, sex, pregnancy,
marital status, sexual orientation, gender identity/expression,
age, disability, genetic information, military service,
covered/protected veteran status or any other federal, state or
local protected class.
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